Field Internship Student Data Acquisition Project. (FISDAP) Airway Practice Exam

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What effect do muscarinic receptors have on heart rate?

Increase heart rate
Decrease heart rate
No effect
Vasodilation

The correct answer is: Decrease heart rate

Muscarinic receptors play a significant role in the regulation of the heart rate, primarily by mediating the effects of the parasympathetic nervous system. When acetylcholine binds to muscarinic receptors located in the heart, this typically leads to a decrease in heart rate. This response is achieved through various mechanisms, including increased K+ conductance and decreased conduction velocity through the atrioventricular (AV) node, which slows down the overall heart rate. Therefore, the correct answer reflects the physiological effect of muscarinic receptor activation, which is to lower the heart rate, emphasizing the crucial role of the parasympathetic nervous system in maintaining cardiac function.